Featured Publications

Characterizing spatial functional microniches with SpaceTravLR

Koushul Ramjattun#, Alyson Wang#, Hannah Lee, Shilpi Giri, Yijia Chen, William A MacDonald, Nathan D Lord, Amanda C Poholek, Youjin Lee, Jishnu Das*

BioRxiv Nov 2025

IL-9 and Blimp-1 protect the transcriptional identity of group 2 innate lymphocytes in allergic asthma

Yibo Zheng, Shilpi Giri, Jinyi Zhang, Yijia Chen, Aaron Yang, Sagar L. Kale, Harshita Beeravolu, Abbe Pannucci, Anthony D. Marinov, Jeremy S. Tilstra, Kun He, Arianna Creech, Daniella M. Schwartz, Rachel A. Gottschalk, Nicolas Bouladoux, Yasmine Belkaid, Anthony R. Cillo, Anuradha Ray & Amanda C. Poholek

Nature Immunology Apr 2026

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Spatial microniches of IL-2 combine with IL-10 to drive lung migratory TH2 cells in response to inhaled allergen

Kun He, Hanxi Xiao, William A. MacDonald, Isha Mehta, Akash Kishore, Augusta Vincent, Zhongli Xu, Anuradha Ray, Wei Chen, Casey T. Weaver, Bart N. Lambrecht, Jishnu Das & Amanda C. Poholek

Nature Immunology Nov 2024

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Systems immunology approaches to study T cells in health and disease

Aaron Yang & Amanda C. Poholek

npj Systems Biology & Applications Oct 2024

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Regulation and Immunotherapeutic Targeting of the Epigenome in Exhausted CD8 T Cell Responses

B Rhodes Ford, Amanda C Poholek

Journal of Immunology Apr 2023

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Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells

B. Rhodes Ford*, Paolo D.A. Vignali*, Natalie L. Rittenhouse*, Nicole E. Scharping*, Ronal Peralta, Konstatinos Lontos, Andrew T. Frisch, Greg M. Delgoffe*, Amanda C. Poholek*

Science Immunology Aug 2022

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Tissue-Specific Contributions to Control of T Cell Immunity

ImmunoHorizons June 2021

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Blimp-1 is Essential for Allergen-induced Asthma and Th2 Cell Development in the Lung

Kun He*, Angela Hettinga*, Sagar L. Kale, Sanmei Hu, Markus M. Xie, Alexander L. Dent, Anuradha Ray, Amanda C. Poholek

Journal of Experimental Medicine May 2020

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Pubmed

Featured Publications

Characterizing spatial functional microniches with SpaceTravLR

Koushul Ramjattun#, Alyson Wang#, Hannah Lee, Shilpi Giri, Yijia Chen, William A MacDonald, Nathan D Lord, Amanda C Poholek*, Youjin Lee*, Jishnu Das*

BioRxiv Nov 2025

IL-9 and Blimp-1 protect the transcriptional identity of group 2 innate lymphocytes in allergic asthma

Spatial microniches of IL-2 combine with IL-10 to drive lung migratory TH2 cells in response to inhaled allergen

Systems immunology approaches to study T cells in health and disease

Regulation and Immunotherapeutic Targeting of the Epigenome in Exhausted CD8 T Cell Responses

Journal of Immunology Apr 2023

Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells

Tissue-Specific Contributions to Control of T Cell Immunity

Blimp-1 is Essential for Allergen-induced Asthma and Th2 Cell Development in the Lung

Koushul Ramjattun#, Alyson Wang#, Hannah Lee, Shilpi Giri, Yijia Chen, William A MacDonald, Nathan D Lord, Amanda C Poholek, Youjin Lee, Jishnu Das*